Bula do remedy Sirturo

the package insert of the medicine Sirturo. Therapeutic class of Antimicobacterianos and Bectericidas. Active principles Bedaquilina.

what For?

Sirturo is indicated for the treatment of pulmonary tuberculosis resistant tb, in adults over 18 years of age.

Dosage

How to use?

Generally, in the first 2 weeks of treatment the recommended dose is 400 mg, 4 tablets of 100 mg per day, administered in single takes. After the first 2 weeks of treatment, the recommended dose should be reduced, going to be the recommended intake of 200 mg, 2 tablets of Sirturo in single takes, administered 3 times per week. For example, from the 3 week treatment Sirturo can be administered will be Monday, Wednesday and Friday of every week. The duration of treatment recommended, is usually of 24 consecutive weeks.

The tablets of Sirturo should be swallowed whole, without breaking or chewing, along with a glass of water and food.

Sirturo should be administered in accordance with medical necessity and in conjunction with other medicines, so as to complete the treatment.

Side Effects

What are the evils that can cause me?

Some of the side effects of Sirturo may include headache, pain in joints, feeling of dizziness, nausea, vomiting, diarrhea, changes in the results of blood work or pain or muscle tenderness without apparent cause.

Contraindications

When should I not use?

Sirturo is contraindicated for patients with allergy to Bedaquilina or other components of the formula.

Pharmacokinetics

How it works?

Sirturo is a prescription medication that has in its composition Bedaquilina, an antibiotic used in the treatment of pulmonary tuberculosis resistant tb, with a bactericidal effect.

The Bedaquilina present in the formula of Sirturo, acts by inhibiting specifically the ATP synthetase micobacteriano, an enzyme essential for the generation of energy in Mycobacterium tuberculosis, which leads to a bactericidal effect on germs of tuberculosis.

Warnings and Precautions

what should I know before using?

Before using Sirturo, you should talk with your doctor if you are pregnant, intending to become pregnant or breastfeeding, you have plotted the abnormal of the heart on the electrocardiogram, malfunction of the heart, a history of diseases or problems in the heart or in the liver, decreased functioning of the thyroid gland, drinking alcoholic beverages regularly, you have Aids, an intolerance to some sugars, especially lactose-intolerant or if you are taking other medicines, including non-prescription drugs or herbal medications. In addition, Sirturo should not be administered to children or adolescents without medical indication.

During treatment with Sirturo should avoid driving vehicles or machinery, because this medicine can cause dizziness.

The treatment with Sirturo should never be stopped without the knowledge of your doctor and the schedules, doses and duration of treatment should be strictly respected.

Overdose

what to do if someone use a larger amount than is recommended?

In the case of taking excessive Sirturo, you must go to the nearest hospital, taking the packaging or package insert for the drug.