The package insert of the medicine Seloken

the package insert of the medicine Seloken. Therapeutic class of Antiarritmicos, Antihypertensives,beta-Blockers and Vasodilators. Active principles Metoprolol.

what For?

Seloken tablet or injectable solution is indicated for high blood pressure, changes in heart rhythm (including especially supraventricular tachycardia), angina pectoris, suspected or myocardial infarction confirmed.

Seloken is also indicated for symptomatic treatment in hyperthyroidism, the changes of cardiac functional with palpitations and in migraine prophylaxis.

adult Use – Use oral Seloken-compressed)

adult Use – Use injectable – Use in the hospital and/or professional (Seloken injectable)

Contraindications

When should I not use?

Seloken should not be used by patients with allergy to metoprolol, other components of the formula or to other beta-blockers.

Dosage

How to use?

Seloken Tablet

The tablets can be taken with food or on an empty stomach.

it is Recommended to individualize the dose. The following doses should be considered as a guide:

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  • Hypertension: the recommended dose in patients with hypertension is 100 to 200 mg daily as a single dose in the morning or divided doses (morning and evening). If necessary, can be added to other drugs anti-hypertensive. The treatment anti-hypertensive long-term daily doses of 100-200 mg of metoprolol has been shown to reduce total mortality, including cardiovascular death sudden, stroke and problems coronary artery in hypertensive patients.
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  • Angina pectoris: The recommended dose is 100 to 200 mg daily, in divided doses (morning and evening). If necessary, may be added other drugs antianginosa.
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  • cardiac Arrhythmias: The recommended dose is 100-200 mg daily, in divided doses (morning and evening). If necessary, can be added to other drug antiarrhythmic.
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  • maintenance Treatment after myocardial infarction: the Treatment of long-term maintenance: in general is 200 mg daily, given in divided doses (morning and evening). This dose has been shown to reduce the risk of mortality (including sudden death) and reduce the risk of reinfarto (also in patients with diabetes mellitus).
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  • Hyperthyroidism: The recommended dose is 150-200 mg daily, divided into 3 to 4 doses. If necessary, the dose may be increased.
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  • Changes in cardiac functional with palpitations: The recommended dose is 100 mg daily as a single dose in the morning. If necessary, the dose may be increased to 200 mg.
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  • migraine Prophylaxis: The recommended dose is 100-200 mg daily, administered in divided doses (morning and evening).

Seloken Injectable Solution

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  • cardiac Arrhythmias: Initially up to 5 mg injected intravenously at a dosage of 1-2 mg/min. The injection can be repeated at intervals of 5 minutes until they obtain a satisfactory answer. Usually a total dose of 10-15 mg is enough. Are unlikely benefits of therapy with doses of 20 mg or more.
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  • Myocardial infarction: Seloken Injectable should be administered intravenously as soon as possible after the onset of symptoms of acute myocardial infarction. Treatment should be initiated in a coronary care unit or similar, immediately after the hemodynamic stabilization of the patient. You should administer 3 injections in bolus of 5 mg each at 2-minute intervals, depending on the hemodynamic conditions of the patient under intensive monitoring. If the patient to tolerate the dose by intravenous total (15 mg), you should go to the maintenance dose of 50 mg orally, 4 times daily, starting 15 minutes after the last intravenous injection. Keeps-if this schema is usually for 48 hours.

maintenance dose is 100 mg of the tartrate of metoprolol (Seloken tablets), orally, 2 times a day (morning and night), or 200 mg Seloken (succinate metoprolol), 1 time a day.

Patients who do not tolerate the dose by intravenous total Seloken Injectable (15 mg) should start oral treatment with care, using a lower dose.

Side Effects

What are the evils that can cause me?

May occur: weakness, dizziness, headache, cold hands and feet, nausea, difficulty breathing, abdominal pain, heart beat slow heart, mixer, diarrhoea and constipation.

Warnings and Precautions

what should I know before using?

Tell your doctor if you have lung problems, circulatory, heart, liver or kidney disease, pheochromocytoma or if you have had symptoms of low blood sugar (hypoglycemia).

Before any surgery, tell the doctor or dentist that you are taking Seloken.

May occur: weakness, dizziness, headache, cold hands and feet, nausea, difficulty breathing, abdominal pain, heart beat slow heart, mixer, diarrhea and constipation. Please inform your doctor.

Check your reaction to the medicine before driving or operating machinery, because, occasionally, may occur dizziness or fatigue.

Drug Interactions

Tell your doctor if you have lung problems, circulatory, heart, liver or kidney disease, pheochromocytoma or if you have had symptoms of low blood sugar (hypoglycemia).

Tell your doctor if you are taking other beta-blockers (including eye drops) or other medicines for the treatment of problems of the heart and circulation (anti-hypertensive drugs, antiarrhythmic drugs), MAO inhibitors (oxidase), alcohol, nsaids, medicines for diabetes, for the treatment of ulcers and anti-depressants.

the result of The treatment may be changed if the metoprolol is taken at the same time as these medicines.