Bula do remedy Sarcoton

the package insert of the medicine Sarcoton. Therapeutic class of the Anti-addictive chemical. Active principlesDisulfiram.

what For?

Sarcoton is indicated as an aid in the treatment of chronic alcoholism. It is not a cure for alcoholism; it simply provides for the individual support to your sincere desire to stop drinking.

adult Use – oral Use

Pharmacokinetics

How it works?

disulfiram, by itself, is a substance relatively non-toxic. However, it changes sharply, the intermediate metabolism of alcohol and causes an increase in the blood concentration of acetaldehyde in up to 5 to 10 times the level achieved when ethanol is given to an individual who has not received prior treatment with disulfiram.

A single dose of disulfiram will begin to produce effect on the metabolism of ethanol within 1 to 2 hours.

The reaction disulfiram-alcohol can occur up to 14 days after the last dose of disulfiram.

Dosage

How to use?

to Administer on the first day of treatment, 2 (two) spoons-measure shallow – approximately 1 g of the powder – one(1) time a day.

In the following days, administer one (1) scoop-measure shallow – approximately 500 mg of the powder – one(1) time a day, for weeks or months, until the patient lose completely the desire of drinking alcoholic beverages, or at the physician’s discretion.

The dosage should not exceed 500 mg of disulfiram daily.

Side Effects

What are the evils that can cause me?

Tell your doctor if you feel eye pain or change in vision, numbness, tingling, pain or weakness in hands or feet.

Contraindications

When should I not use?

Sarcoton is contraindicated to patients sensitive to disulfiram or other tiuranos (as contained in rubber, pesticides and fungicides).

Warnings and Precautions

what should I know before using?

Sarcoton in pregnancy and breast feeding: tell your doctor the occurrence of pregnancy during treatment or after its termination.

Tell your doctor if you are breast-feeding.

Some cases of birth defects have been reported in children of mothers who received disulfiram during pregnancy. Studies have reported embriotoxicidade of disulfiram in animals. With this, the safety of drug use during pregnancy has not yet been determined and therefore, the therapy with disulfiram in pregnant women, should be evaluated by the doctor regarding the risk-benefit ratio.

there are No studies that prove the safety of the product during lactation. The doctor must choose the treatment interruption or the cessation of breastfeeding.

Sarcoton should only be administered after 12 hours from the last ingestion of alcohol by the patient.

should Not be administered to patients in state of alcohol intoxication, or without his full knowledge.

do Not stop treatment without the knowledge of your doctor.

there is No information available as to the effect of disulfiram in elderly patients. however, patients with advanced age are more likely to experience some renal dysfunction, and one should exercise caution during therapy with disulfiram. still, elderly patients with heart disease or strokes, may not tolerate the hypotension resulting from the reaction disulfiram – alcohol, as well as younger patients.

The ingestion of alcohol by individuals previously treated with Sarcoton, gives rise to the signs and symptoms of acute, known as reaction disulfiram-alcohol, characterized by: feeling face, hot, redness in face, headache intense, difficulty breathing, nausea, vomiting, sweating, thirst, weakness, vertigo, blurred vision. The facial flushing is replaced by pallor, followed by a drop in blood pressure.

The reaction disulfiram-alcohol can occur up to 14 days after the administration of Sarcoton if the intake of alcohol or products that contain alcohol.

it Is necessary that the patient learn to prevent forms of disguised alcohol as sauces, spices, vinegar, some types of medications that contain alcohol in their formulation, as some syrups and even lotions after shaving.

Tell your doctor if you have displayed one of the following situations: contact dermatitis eczematous allergic, cardiovascular disorders, depression, diabetes mellitus, epilepsy, or other changes convulsive, malfunction of liver or cirrhosis, hypothyroidism, psychoses, pulmonary function impairment, severe renal dysfunction.

The serum concentration of cholesterol may increase with dose of 500 mg of disulfiram a day.

The urinary concentration of the acid vanililmandélico (VMA) may decrease during therapy with disulfiram.

Drug Interactions