the package insert of the medicine Rulid 300 mg. Therapeutic class of Antibacterial. Active principlesRoxithromycin.
As the antibacterial germs defined above as sensitive in infections, especially in otolaryngology, pulmonology, dermatology; genital infections, except those caused by the Gonococcus; in prophylaxis of meningococcal meningitis in contactantes.
When should I not use?
Allergy to macrolides, concomitant use of ergot alkaloids.
How to use?
A tablet of 300 mg per day, in a single taken on an empty stomach, preferably, before meals, during 11 days, or at the physician’s discretion.
What are the evils that can cause me?
Manifestations of the digestive tract: Nausea, vomiting, epigastralgias, diarrhea. Cutaneous manifestations of nature allergic. Transitory increase possible in transaminases, and may evolve unusually for a cholestatic hepatitis.
Warnings and Precautions
what should I know before using?
In case of hepatic insufficiency, the administration of RULID (roxithromycin) is not recommended. If it is necessary, then it must be accompanied by liver tests regular and, eventually, a reduction of dosage. The renal elimination of the molecule active is small, which allows you to keep the dosage in case of renal failure. In the elderly, the half-life is lengthened. However, plasma concentrations peak and the area under the curve (in the state of balance of roxithromycin) do not differ from those obtained in young people. Therefore, it is not necessary to modify the dosing in the elderly. Pregnancy: The results of studies conducted in animals have not shown teratogenic effects. In the absence of clinical data, these experimental results do not allow to predict malformations in the human species. Breast-feeding: The passage of the drug into the breast milk is very low.
what to do if someone use a larger amount than is recommended?
In the dog, after oral administration of a single dose of 2,000 mg/kg were observed: vomiting, abundant, diarrhea, apathy, and decreased motor activity. In case of overdose proceed to gastric lavage and symptomatic treatment. There is no specific antidote.