the package insert of the medicine Rulid 150 mg. Therapeutic class of the Systemic Antibiotics. Active principles Roxithromycin. Sale under medical prescription.
As the antibacterial germs defined above as sensitive in infections, notably in otorhinolaryngology, pneumonologia, dermatology; genital infections, except those caused by the gonococcus; in the prophylaxis of meningitis menigocócica in contactantes.
When should I not use?
Allergy to macrolides, simultaneous use of alkaloids vasoconstrictors of ergot (ergotamine and dihydroergotamine).
How to use?
AEm adults, 300 mg per day, divided in 1 tablet empty stomach and 1 tablet at night (12 in 12 hours), preferably before meals, for 10 days, or at the physician’s discretion.
What are the evils that can cause me?
Manifestations of the digestive tract: nausea, vomiting, epigastralgias, diarrhea.
the uncomplicated skin Manifestations of nature allergic.
transitory Increase possible in transaminases, and may evolve unusually for a hepatitis colestásica.
Warnings and Precautions
what should I know before using?
In case of hepatic insufficiency, the administration of the RULID (Roxithromycin) is not recommended. If it is necessary, then it must be accompanied by liver tests regular and, eventually, reduction of dosage.
The renal elimination of the molecule active is small, which allows you to keep the dosage in case of renal failure.
In the elderly, the half-life is lengthened. However, after repeated administration of 150 g every 12 hours, plasma concentrations peak and the area under the curve (in the steady state, between two outlets of Roxithromycin) do not differ from those obtained in young people. Therefore it is not necessary to modify the dosing in the elderly.
Pregnancy: the results of studies conducted in animals have not shown teratogenic effects. In the absence of clinical data, these experimental results do not allow to predict malformation in the human species.
Breastfeeding: the pay of the drug to the breast milk is very low.
what to do if someone use a larger amount than is recommended?
In the dog, after oral administration of a single dose of 2000 mg/kg were observed: vomiting, abundant, diarrhea, apathy, and decreased motor activity.
In cases of overdose will gastric lavage and symptomatic treatment. there is no specific antidote.