The package insert of the medicine Quadrihexal

the package insert of the medicine Quadrihexal. Therapeutic class of Topical Antibiotics and Corticosteroids Topics. Active principles Valerato de Betamethasone, Clioquinol, Sulfate Gentamicin andTolnaftate. Sale under medical prescription.

what For?

Preparation of dermatological, topical highly effective in the treatment of numerous affections


When should I not use?

In the cases of lesions with tuberculosis (tb) of the skin, herpes simplex, acute vacínia and chicken pox, the
patients with a history of hypersensitivity reactions to any of its components.


How to use?

A small amount of quadrihexal should be applied gently on the lesions, 2 or 3
Times a day. the frequency of application should be based on the severity of the disorder. the length of the
Treatment will be determined by the response of the patient. in cases of tinea pedis may be required
Longer treatment (2 to 4 weeks). there is no information about local irritation or sensitization with
Application of this preparation.

Side Effects

What are the evils that can cause me?

local Reactions, reported with the use of topical corticosteroid, especially under
occlusive dressings, include: burning, itching, irritation, dryness, folliculitis, hypertrichosis, eruptions
acneiformes, hypopigmentation, perioral dermatitis, dermatitis allergic contact, maceration of the skin, infection
secondary, skin atrophy, stretch marks, and miliárias. Skin rashes, irritation and hypersensitivity have been reported
with the topical use of the sulfate of gentamicin and clioquinol and rarely with tolnaftate.

Warnings and Precautions

what should I know before using?

General: The absorption of QuadriHEXAL will be greater than if the surfaces extended from the body
are treated or if the technical stop is employed, therefore, take appropriate precautions in these
conditions or when extended use of the product, particularly in children of low age.

to Discontinue treatment in case of irritation, sensitization or superinfection in these cases to establish therapy
appropriate. The systemic absorption of clioquinol may interfere with testing of thyroid function. The test
ferric chloride for phenylketonuria can reveal result falsely positive if the clioquinol is present in the
urine. Stains light clothing may occur due to the clioquinol. QuadriHEXAL is not appropriate to
use ophthalmic.

Use in pregnancy:. Should only be administered during pregnancy if the benefits
potential justify the potential risks to the fetus.

Use in breastfeeding: you Must decide between
interrupt breastfeeding or to discontinue the drug, taking into account the
the importance of the same to the mother.

Use in paediatrics: there have Been reported suppression of the axis hipotálamohipófise-
the supra-renal disease, Cushing’s syndrome, delayed growth, slow weight gain, and hypertension
intracranial in children receiving corticosteóide topic. The manifestations of suppression of the adrenal in
children include a low level of cortisol plasma level and absence of response to stimulation with ACTH. The
manifestations of intracranial hypertension include fontanelles tense, headache and papilledema bilaterally.


Dermatological Cream 20 g


Sale prescription


Valerato de betamethasone
Sulfate gentamicin
Tolnaftate and Clioquinol
In the Registry-MS: 1.0047.0303




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