Bula do remedy Exjade

the package insert of the medicine Exjade. Therapeutic class of Chelating Agents and Antidotos. Active principles Deferasirox.

what For?

Exjade 125, 250 or 500 mg is indicated for the treatment of iron overload caused by blood transfusions or by the syndrome of thalassemia intermedia in children and adults.

Dosage

How to use?

The quantities of Exjade to use, and the duration of treatment should be given by your doctor, since they depend on the body weight, the individual needs of treatment and the individual response of each patient to treatment.

The Exjade tablets must be taken 1 time per day, preferably always at the same hour, and on an empty stomach. After ingestion of the tablets, you must wait 30 minutes before ingesting food.

The Exjade tablets must be administered in the following way: begin by placing the recommended dose by your doctor in a glass of water, apple juice or orange and stir until the complete dissolution of the tablets. After the complete dissolution of the tablets, should drink all the content, add a cup of water to the juice to remaining in the cup, shake well and consume the content again.

Side Effects

What are the evils that can cause me?

Some of the side effects of Exjade may include changes in tests of kidney function, nausea, vomiting, pain in the abdomen, feeling of full stomach, constipation, bad digestion, hives on the skin, headache, itching and presence of proteins in the urine.

Contraindications

When should I not use?

Exjade is contraindicated for patients with diseases or kidney problems, patients in treatment with other medicine chelation of iron, in the advanced stage of the syndrome mielodisplástico or with advanced cancer and for patients with allergy to Deferasirox or to other components of the formula.

Pharmacokinetics

How it works?

Exjade is a medicine that has in its composition of Deferasirox, a compound which is a chelator of iron, that is, that it is able to “trap” the ions of iron, thus helping to remove the excess iron from the body. Thus, Exjade helps to treat cases of iron overload, promoting the excretion of this iron, mainly in the faeces.

Warnings and Precautions

what should I know before using?

Before using Exjade, you should talk with your doctor if you are pregnant or nursing, have more than 65 years, have diseases or problems in the kidney, liver or heart, an intolerance to some sugars, decreased volume of urine, vomiting with blood, abdominal pain after the meal or after taking the dose of Exjade, have heartburn, low levels of platelets or white cells in the results of the blood tests, blurred vision, vomiting or diarrhea, or if you are in treatment with other medications.

During the treatment, if you feel symptoms such as hives on the skin, trouble breathing, dizziness, swelling of the face, throat, eyes, or mouth, redness of the skin, blisters on the lips, eyes or mouth, skin peeling, sore throat, drowsiness, abdominal pain, yellowing of the skin or eyes, or dark urine, you should consult your doctor as soon as possible.

During treatment with Exjade should avoid driving vehicles or machinery, because this medicine can cause dizziness.

treatment with Exjade should never be stopped without the knowledge of your doctor and the schedules, doses and duration of treatment should be strictly respected.

Overdose

what to do if someone use a larger amount than is recommended?

In the case of taking excessive Exjade, you must go to the nearest hospital, taking the packaging or package insert for the drug.