The package insert of the medicine Cimetina

the package insert of the medicine Cimetina. Therapeutic class of Antiulcerosos. Active principles Cimetidine.

what For?

In the reduction of the acidity of the gastric secretion, being effective in the treatment of gastric ulcer and duodenal.


When should I not use?

known Hypersensitivity to any component of the formula, pregnancy and lactation.


How to use?

Adults: the recommended dose in the treatment of duodenal ulcer active is 800 mg/day in a single dose or in 2 doses of 400 mg. the complete healing usually occurs in 4 weeks, and symptomatic relief arises commonly within a few days. in patients whose ulcers have not healed in 4 weeks, this is usually obtained when the treatment is maintained for 2 or 4 weeks. after the remission of the ulcer, in patients with a history of recurrence, it is recommended that maintenance treatment with lower dose (400 mg) to prevent recurrence. cimetina has been used safely in these patients for up to 5 years. dosage the usual cimetina for this condition is 400 mg 2 times a day or 200 mg 3 times daily and 400 mg at bedtime. in the majority of patients, complete healing occurs in 4 weeks, but the pain relief occurs more
Quickly. after the remission of the frame ulceroso, maintenance treatment is 400 mg, significantly reduced the recurrences.

In mild cases and moderate esophagitis peptic dose is 400 mg 2 times a day. the usual dose ranges from 800-1600 mg/day in 2 or 4 outlets for up to 12 weeks. the treatment of the disorders, pathological hypersecretion should be adjusted individually, but the initial dosing is usually 200 mg 3 times daily and 400 mg at bedtime.

The recommended dose for conditions not ulcerosas related with stomach acid is 200 mg 4 times a day. the relief of symptoms dispéptica generally arises within a treatment period of 1 to 4 weeks. the
Dose total daily time should not exceed 2400 mg. the dose should be decreased in patients with renal insufficiency. the recommended doses are correlated to the clearance or plasma clearance of creatinine.

In patients undergoing dialysis cimetina should be administered as soon as finish the hemodialysis.

The levels are not altered by peritoneal dialysis.

Children: it is recommended the following dosing schedule divided into taken every 4 or 6 hours.

neonates: 10-15 mg/kg/day.

Under 1 year: 20 mg/kg/day.

1 to 12 years: 20-25 mg/kg/day.

Warnings and Precautions

what should I know before using?

Before the establishment of the treatment of a gastric ulcer, it is necessary to exclude possible malignancy, because their symptoms may respond to therapy with H2 antagonists. The use of anti-secretory this class favors the development of bacterial intragastric by a decrease in the acidity gastric. The CIMETINA inhibits certain mechanisms enzyme to the liver and may increase the action of certain drugs, in a few cases this has meant the clinic. Include in these cases, the anticoagulants of type warfarin, phenytoin, theophylline, and lidocaine, drugs metabolized in the liver.


20 tablets 200 m tog




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