the package insert of the medicine Cholib. Therapeutic class of the Anti-dyslipidemia. Active principlesSimvastatin and Fenofibrate.
Cholib tablets is a drug indicated to lower levels of bad cholesterol and triglycerides in the blood, while increasing levels of good cholesterol.
Oral Use – Adult Use
How to use?
Cholib Tablets may be administered in doses of 145 mg/ 20 mg and 145 mg/ 40 mg, and in both cases, the recommended dose for adults is 1 tablet per day.
The tablets should be swallowed whole, without breaking or chewing, with a glass of water and can be administered with or without food.
What are the evils that can cause me?
Some of the side effects of Cholib include: pain, tenderness, or muscle weakness, allergic reactions, pain, or inflammation in the joints, inflammation of blood vessels, unusual bruising, skin eruptions and swelling, hives, increased sensitivity of skin to sunlight, fever, flushing, shortness of breath, and malaise, rash, joint disorders, and effects on white blood cells, muscle cramps or sore muscles or weak, stomach pain, pain in the chest and feeling of breathlessness, pain, redness or swelling in the legs or yellowing of skin and whites of the eyes – jaundice or increased liver enzymes.
When should I not use?
The administration of Cholib is contraindicated in: pregnant or nursing women, children, and adolescents under the age of 18 years, patients allergic to Fenofibrate or to Simvastatin or any component of the formula, the patients who are allergic to peanuts, peanut oil, soy lecithin, Statins, or other substances, patients with a history of allergic reactions to the sun or to UV rays when you were taking other medications, patients with liver problems or gallbladder, patients with pancreatitis, patients with kidney disease and the patients with a history of muscle problems during treatment to reduce the levels of fat in the blood.
How it works?
cholesterol is one of the many substances that are fat found in the blood, and total cholesterol can be divided into two forms of cholesterol, LDL cholesterol, and HDL, or bad cholesterol and good cholesterol.
The cholesterol LDL is usually called bad because it accumulates in the walls of the arteries forming a plaque, which over time grows and may lead to clogging of the arteries. On the other hand, the HDL cholesterol is known as good cholesterol, because it prevents the bad cholesterol from building up in the walls of the arteries and because it has a protective action against heart disease. Triglycerides are another fat substance present in the blood that can increase the risk of heart diseases.
Cholib is a medicine that has in its composition two active substances, Fenofibrate and Simvastatin, both responsible for reducing the levels of total cholesterol in blood, LDL cholesterol, and Triglycerides, at the same time that are able to increase the levels of HDL cholesterol in the blood.
Warnings and Precautions
what should I know before using?
Before taking Cholib, you should speak with your doctor or pharmacist if: you have diabetes, you are intolerant to some sugars such as lactose and sucrose, are taking other medicines, including medicines without a prescription and herbal medicines, have hypothyroidism, you are waiting for a surgery, consume alcoholic beverages regularly and in excess, you have pain in the chest and feeling of breathlessness, has a severe lung disease or if you are taking or have taken Acid Fusídico in the last 7 days.
Before you start treatment with Cholib, it is advised that you consult with your doctor so that you can be for blood tests to evaluate the state of your muscles and liver.During treatment with Cholib, patients with diabetes or prone to diabetes should be regularly monitored.
The treatment with Cholib should be accompanied by a diet of low fat with a practice of regular exercise.
During treatment with Cholib should not drink grapefruit juice, since this juice can increase your risk of developing muscle problems.
what to do if someone use a larger amount than is recommended?
In the case of taking excessive Cholib, you must go to the nearest hospital, taking the packaging or package insert for the drug.
what should I do when I forget to use this medicine?
in Case of the neglect of the administration of a dose of Cholib should skip the missed dose, taking only the dose of the next day on time as usual. The dose of Cholib should never be administered to double or at times very near.
Cholib must not be given together with some drugs such as: Acid Fusídico, Danazol, Ciclosporin, Itraconazole, Ketoconazole, Fluconazole, Posaconazole, HIV protease inhibitors such as Indinavir, Nelfinavir, Ritonavir and Saquinavir, Erythromycin, Clarithromycin, or Telithromycin, Nefazodone, Fibrates or Statin.
Before you start treatment with Cholib should talk to your doctor or pharmacist if you are taking or if you have taken any of the following drugs: doses of a gram of Niacin, Colchicine, anticuagulantes as Warfarin, Fluindione, Phenprocoumone or Acenocoumarol, Pioglitazone or Rifampicin.
Abbott Healthcare SAS: Telf. 04 74 45 54 42
Other drugs prescribed to reduce cholesterol levels in the blood are:Sivastin, Sinvascor, Lovacor, Sinvatrox and Mivalen.
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